Luminoimmunometric Assay of Tissue Polypeptide Antigen (Tpa) and Cancer Antigen 125 (Ca-125) in Breast Cancer Patients | Zendy

O. El-Ahmady | Zendy; Halim A.-B. | Zendy; Sanaa Eissa | Zendy

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Luminoimmunometric Assay of Tissue Polypeptide Antigen (Tpa) and Cancer Antigen 125 (Ca-125) in Breast Cancer Patients

Author(s) -

O. El-Ahmady,

Halim A.-B.,

Sanaa Eissa

Publication year - 1993

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/1993/682804

Subject(s) - antigen , breast cancer , cancer , cancer antigen , medicine , microbiology and biotechnology , ca 15 3 , cancer research , pathology , biology , immunology , ca15 3

Serum TPA and CA-125 were determined in 86 individuals (66 with breast cancer representing the different stages and grades of the disease and 20 normal healthy controls). TPA and CA-125 were estimated using the LIA reagents supplied by BYK Sangtec. TPA showed sensitivity rates of 31.8%, 42.4% and 51.5% while CA-125 showed sensitivities of 16.3%, 18.6% and 25.6% at specificity levels of 100%, 95% and 90% respectively. Combined determination of the two markers resulted in some improvement in sensitivity. For follow-up of breast cancer patients after surgery both markers were of value and showed near-identical patterns.

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