Thrombotic Thrombocytopenic Purpura Associated with the Acquired Immune Deficiency Syndrome
Author(s) -
Anand Kumar,
Jean Wang,
David Sutton,
Eric J. Bow
Publication year - 1990
Publication title -
canadian journal of infectious diseases and medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1918-1493
pISSN - 1712-9532
DOI - 10.1155/1992/903715
Subject(s) - thrombotic thrombocytopenic purpura , plasmapheresis , medicine , immunology , immune system , thrombocytopenic purpura , pathogenesis , immunopathology , human immunodeficiency virus (hiv) , evans syndrome , platelet , antibody , autoimmune hemolytic anemia
A bisexual male presented with acute thrombotic thrombocytopenic purpura (TTP) in association with established acquired immune deficiency syndrome. The patient had classic clinical and laboratory findings of TTP and responded well to plasmapheresis therapy. Previously reported cases of TTP in association with human immunodeficiency virus (HIV) infection are briefly reviewed. Basic concepts in the pathogenesis of TTP are examined in reference to HIV infection.
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