Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report | Zendy

Franzjosef Schweiger | Zendy

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Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report

Author(s) -

Franzjosef Schweiger

Publication year - 1990

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/1990/325186

Subject(s) - collagenous colitis , barium enema , medicine , colonoscopy , microscopic colitis , diarrhea , colitis , gastroenterology , chronic diarrhea , enema , biopsy , pathology , colorectal cancer , inflammatory bowel disease , cancer , disease

Collagenous colitis is a clinicopathologic syndrome which presentsas chronic, watery, nonbloody diarrhea. Colonic biopsies characteristicallyshow a thick subepithelial collagen band. Barium enema and colonoscopygenerally fail to establish the diagnosis. This case report provides evidence forhistologic progression over time, pancolonic involvement and the presence ofextraintestinal features of collagenous colitis. The reported patient showed noresponse to 5-aminosalicylic acid. Colonoscopic biopsies in cases of chronicdiarrhea can save the patient repeated, uncomfortable and costly investigations

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