z-logo
open-access-imgOpen Access
Exacerbation of Ulcerative Colitis following Administration of 5-ASA Enemas
Author(s) -
Barbara Young,
Robin S. McLeod,
Zane Cohen
Publication year - 1989
Publication title -
canadian journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
eISSN - 2291-2797
pISSN - 2291-2789
DOI - 10.1155/1989/461926
Subject(s) - medicine , sulfasalazine , diarrhea , ulcerative colitis , exacerbation , enema , nausea , vomiting , gastroenterology , bloody diarrhea , oral administration , abdominal pain , colectomy , disease
A 33-year-old female with a 15 year history of ulcerative colitispresented with worsening diarrhea following colectomy and ileorectal anastomosissix months previously. Following administration of 5-ASA enemas (Salofalk).the patient developed abdominal cramps. nausea and vomiting. and severe diarrhearesulting in hypotension. Symptoms abated quickly when the 5-ASA enemas,were discontinued. Although diarrhea and abdominal cramps have beendescribed previously as side effects of oral sulfasalazine. oral 5-ASA and sulfasalazineenemas, this is the first report of these symptoms occurring following administrationof 5-ASA enemas

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom