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Hypothalamic Hypogonadism in Hemochromatosis: A Case Report
Author(s) -
Igor Matwijiw,
Gerald D. Iliffe,
Adi Mehta,
Charles Faiman
Publication year - 1988
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/1988/214932
Subject(s) - hemochromatosis , hypogonadotropic hypogonadism , medicine , cirrhosis , hereditary hemochromatosis , endocrine system , hypothalamic disease , pediatrics , disease , endocrinology , hormone
A 42-year-old man developed hypogonadotropic hypogonadism dueto primary hemochromatosis. Endocrine evaluation indicated a hypothalamic defectin the control of gonadotropin secretion. Although cirrhosis was present on liverbiopsy, ocher major features of the hemochromatosis syndrome were not manifest.Patients with hemochromacosis arc now being diagnosed at earlier stages of disease.Clinicians should be alert to possible early development of hypothalamopituitarydysfunction and should be prepared co perform derailed endocrinological investigationsin such patients

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