Decoding Calcium Signaling Across the Nucleus | Zendy

A. G. de Oliveira | Zendy; Erika S. Guimarães | Zendy; Lídia M. Andrade | Zendy; Gustavo Batista Menezes | Zendy; M. Fátima Leite | Zendy

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Decoding Calcium Signaling Across the Nucleus

Author(s) -

A. G. de Oliveira,

Erika S. Guimarães,

Lídia M. Andrade,

Gustavo Batista Menezes,

M. Fátima Leite

Publication year - 2014

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00056.2013

Subject(s) - nucleus , calcium , decoding methods , calcium signaling , biology , neuroscience , signal transduction , microbiology and biotechnology , medicine , computer science , algorithm

Calcium (Ca(2+)) is an important multifaceted second messenger that regulates a wide range of cellular events. A Ca(2+)-signaling toolkit has been shown to exist in the nucleus and to be capable of generating and modulating nucleoplasmic Ca(2+) transients. Within the nucleus, Ca(2+) controls cellular events that are different from those modulated by cytosolic Ca(2+). This review focuses on nuclear Ca(2+) signals and their role in regulating physiological and pathological processes.

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