Open AccessThe Ins and Outs of Iron Homeostasis
Author(s) -
Adriana Donovan,
Cindy N. Roy,
Nancy C. Andrews
Publication year - 2006
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00052.2005
Subject(s) - iron homeostasis , homeostasis , microbiology and biotechnology , biology , biochemistry , metabolism
Iron is an essential element that is toxic when it accumulates in excess. Intricate regulatory mechanisms have evolved to maintain iron homeostasis within cells and between different tissues of complex organisms. This review discusses the proteins involved in iron transport and storage and their regulation in health and disease.
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