Obesity Impacts Fever and Sickness Behavior During Acute Systemic Inflammation
Author(s) -
Christoph Rummel,
J. Bredehöft,
Jelena Damm,
Hanna Schweighöfer,
Verena Peek,
Lois M. Harden
Publication year - 2016
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00049.2015
Subject(s) - systemic inflammation , inflammation , obesity , medicine , sickness behavior , diabetes mellitus , disease , immunology , intensive care medicine , endocrinology
Obesity is reaching dramatic proportions in humans and is associated with a higher risk for cardiovascular disease, diabetes, and cognitive alterations, and a higher mortality during infection and inflammation. The focus of the present review is on the influence of obesity on the presentation of fever, sickness behavior, and inflammatory responses during acute systemic inflammation.
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