Extracellular Vesicles: Exosomes and Microvesicles, Integrators of Homeostasis
Author(s) -
Philip D. Stahl,
Graça Raposo
Publication year - 2019
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00045.2018
Subject(s) - microvesicles , microbiology and biotechnology , endosome , microvesicle , homeostasis , vesicle , extracellular , intracellular , biology , exocytosis , extracellular vesicles , exosome , secretion , chemistry , membrane , biochemistry , microrna , gene
Extracellular vesicles (EVs), cell-derived membrane structures, are secreted after fusion of endosomes with the plasma membrane (exosomes) or shed from the plasma membrane (microvesicles). EVs play a key role both in physiological balance and homeostasis and in disease processes by their ability to participate in intercellular signaling and communication.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom