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How Does the Kidney Filter Plasma?
Author(s) -
Karl Tryggvason,
Jorma Wartiovaara
Publication year - 2005
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00045.2004
Subject(s) - filtration (mathematics) , slit diaphragm , podocyte , diaphragm (acoustics) , filter (signal processing) , renal function , kidney , urine , chemistry , biology , endocrinology , computer science , physics , mathematics , proteinuria , statistics , acoustics , loudspeaker , computer vision
The kidneys filter the plasma in special filtration units-glomeruli-and thereby excrete low-molecular-weight waste products into the urine. The mechanisms of glomerular filtration have been a matter of controversy for several decades, but recent data have revealed new details about the molecular nature of the filter and have demonstrated a central role for the podocyte slit diaphragm in the filtration process.

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