Endothelial Fatty Acid Transport: Role of Vascular Endothelial Growth Factor B
Author(s) -
Carolina E. Hagberg,
Annika Mehlem,
Annelie Falkevall,
Lars Muhl,
Ulf Eriksson
Publication year - 2013
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00042.2012
Subject(s) - vascular endothelial growth factor b , vascular endothelial growth factor c , endothelium , vascular endothelial growth factor , microbiology and biotechnology , vascular endothelial growth factor a , biology , transporter , fatty acid , biochemistry , chemistry , vegf receptors , endocrinology , cancer research , gene
Dietary lipids present in the circulation have to be transported through the vascular endothelium to be utilized by tissue cells, a vital mechanism that is still poorly understood. Vascular endothelial growth factor B (VEGF-B) regulates this process by controlling the expression of endothelial fatty acid transporter proteins (FATPs). Here, we summarize research on the role of the vascular endothelium in nutrient transport, with emphasis on VEGF-B signaling.
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