High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions | Zendy

David J. Bishop | Zendy; Javier Botella | Zendy; Amanda J. Genders | Zendy; Matthew JC. Lee | Zendy; Nicholas J. Saner | Zendy; Jujiao Kuang | Zendy; Xu Yan | Zendy; Cesare Granata | Zendy

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High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions

Author(s) -

David J. Bishop,

Javier Botella,

Amanda J. Genders,

Matthew JC. Lee,

Nicholas J. Saner,

Jujiao Kuang,

Xu Yan,

Cesare Granata

Publication year - 2018

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00038.2018

Subject(s) - mitochondrial biogenesis , biogenesis , biology , neuroscience , psychology , mitochondrion , political science , genetics , gene

It is well established that different types of exercise can provide a powerful stimulus for mitochondrial biogenesis. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the efficacy of high-intensity exercise to promote mitochondrial biogenesis in humans. The purpose of this review is to examine current controversies in the field and to highlight some important methodological issues that need to be addressed to resolve existing conflicts.

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