Open AccessNeural Mechanisms of Cardioprotection
Author(s) -
Andrey Gourine,
Alexander V. Gourine
Publication year - 2014
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00037.2013
Subject(s) - cardioprotection , reflex , medicine , neuroscience , ischemia , reperfusion injury , ischemic preconditioning , myocardial infarction , infarction , cardiology , anesthesia , biology
This review highlights the importance of neural mechanisms capable of protecting the heart against lethal ischemia/reperfusion injury. Increased parasympathetic (vagal) activity limits myocardial infarction, and recent data suggest that activation of autonomic reflex pathways contributes to powerful innate mechanisms of cardioprotection underlying the remote ischemic conditioning phenomena.
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