Intercellular Communication in Atherosclerosis | Zendy

Laurent Burnier | Zendy; Pierre Fontana | Zendy; Anne AngelilloScherrer | Zendy; Brenda R. Kwak | Zendy

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Intercellular Communication in Atherosclerosis

Author(s) -

Laurent Burnier,

Pierre Fontana,

Anne AngelilloScherrer,

Brenda R. Kwak

Publication year - 2009

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00036.2008

Subject(s) - gap junction , intracellular , homeostasis , biology , pathophysiology , microbiology and biotechnology , disease , cell signaling , cell , connexin , cell junction , neuroscience , pathology , signal transduction , medicine , endocrinology , genetics

Cell-to-cell communication is a process necessary for physiological tissue homeostasis and appears often altered during disease. Gap junction channels, formed by connexins, allow the direct intercellular communication between adjacent cells. After a brief review of the pathophysiology of atherosclerosis, we will discuss the role of connexins throughout the different stages of the disease.

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