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Neural Control of Walking in People with Parkinsonism
Author(s) -
Daniel S. Peterson,
Fay B. Horak
Publication year - 2016
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00034.2015
Subject(s) - gait , parkinsonism , parkinson's disease , basal ganglia , slowness , neuroscience , physical medicine and rehabilitation , gait disturbance , cerebellum , disease , motor control , psychology , medicine , central nervous system , pathology , physics , quantum mechanics
People with Parkinson's disease exhibit debilitating gait impairments, including gait slowness, increased step variability, and poor postural control. A widespread supraspinal locomotor network including the cortex, cerebellum, basal ganglia, and brain stem contributes to the control of human locomotion, and altered activity of these structures underlies gait dysfunction due to Parkinson's disease.

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