Cardiometabolic Features of Polycystic Ovary Syndrome: Role of Androgens
Author(s) -
Licy L. Yanes Cardozo,
Damián G. Romero,
Jane F. Reckelhoff
Publication year - 2017
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00030.2016
Subject(s) - polycystic ovary , endocrine system , endocrinology , medicine , androgen excess , ovary , testosterone (patch) , insulin resistance , physiology , obesity , hormone
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects reproductive-age women. Hyperandrogenemia is present in a significant fraction (~80%) of women with PCOS. Increased prevalence of cardiometabolic risk factors is frequently observed in PCOS women. The present review aims to highlight the key role of androgens in mediating the negative cardiometabolic profile observed in PCOS women.
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