Mechanisms of Exercise-Induced Cardioprotection | Zendy

Scott K. Powers | Zendy; Ashley J. Smuder | Zendy; Andreas N. Kavazis | Zendy; John C. Quindry | Zendy

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Mechanisms of Exercise-Induced Cardioprotection

Author(s) -

Scott K. Powers,

Ashley J. Smuder,

Andreas N. Kavazis,

John C. Quindry

Publication year - 2014

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00030.2013

Subject(s) - cardioprotection , medicine , cardiology , coronary artery disease , pathological , disease , ischemia , reperfusion injury , cause of death

Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.

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