Sex-Based Differences in Skeletal Muscle Kinetics and Fiber-Type Composition | Zendy

Kaylan M. Haizlip | Zendy; Brooke C. Harrison | Zendy; Leslie A. Leinwand | Zendy

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Sex-Based Differences in Skeletal Muscle Kinetics and Fiber-Type Composition

Author(s) -

Kaylan M. Haizlip,

Brooke C. Harrison,

Leslie A. Leinwand

Publication year - 2015

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00024.2014

Subject(s) - skeletal muscle , myosin , endocrinology , medicine , biology , estrogen , testosterone (patch) , composition (language) , hormone , fiber type , microbiology and biotechnology , linguistics , philosophy

Previous studies have identified over 3,000 genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.

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