Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium | Zendy

Livius V. d’Uscio | Zendy; Tongrong He | Zendy; Zvonimir S. Katušić | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium

Author(s) -

Livius V. d’Uscio,

Tongrong He,

Zvonimir S. Katušić

Publication year - 2016

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00021.2016

Subject(s) - amyloid precursor protein , endothelium , microbiology and biotechnology , biology , pathological , protein precursor , pathology , gene , biochemistry , medicine , endocrinology , alzheimer's disease , disease

Amyloid precursor protein (APP) is evolutionary conserved protein expressed in endothelial cells of cerebral and peripheral arteries. In this review, we discuss mechanisms responsible for expression and proteolytic cleavage of APP in endothelial cells. We focus on physiological and pathological implications of APP expression in vascular endothelium.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research