Open AccessHypoxia Signaling in Vascular Homeostasis
Author(s) -
Glenn Marsboom,
Jalees Rehman
Publication year - 2018
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00018.2018
Subject(s) - hypoxia (environmental) , vascular permeability , homeostasis , inflammation , biology , medicine , microbiology and biotechnology , immunology , endocrinology , chemistry , organic chemistry , oxygen
Hypoxia signaling in the vasculature controls vascular permeability, inflammation, vascular growth, and repair of vascular injury. In this review, we summarize recent insights in this burgeoning field and highlight the importance of studying the heterogeneity of hypoxia responses among individual patients, distinct vascular beds, and even individual vascular cells.
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