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Running Changes the Brain: the Long and the Short of It
Author(s) -
Carmen Vivar,
Henriette van Praag
Publication year - 2017
Publication title -
physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.14
H-Index - 125
eISSN - 1548-9213
pISSN - 1548-9221
DOI - 10.1152/physiol.00017.2017
Subject(s) - neurogenesis , neuroscience , acetylcholine , hippocampus , neurotransmitter , glutamate receptor , neurotransmitter systems , neuron , afferent , cognition , psychology , biology , central nervous system , dopamine , endocrinology , biochemistry , receptor
Exercise is a simple intervention that profoundly benefits cognition. In rodents, running increases neurogenesis in the hippocampus, a brain area important for memory. We describe the dynamic changes in new neuron number and afferent connections throughout their maturation. We highlight the effects of exercise on the neurotransmitter systems involved, with a focus on the role of glutamate and acetylcholine in the initial development of new neurons in the adult brain.

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