ORAI Calcium Channels | Zendy

Mohamed Trebak | Zendy; James W. Putney | Zendy

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ORAI Calcium Channels

Author(s) -

Mohamed Trebak,

James W. Putney

Publication year - 2017

Publication title -

physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.14

H-Index - 125

eISSN - 1548-9213

pISSN - 1548-9221

DOI - 10.1152/physiol.00011.2017

Subject(s) - calcium signaling , calcium , microbiology and biotechnology , posttranslational modification , chemistry , voltage dependent calcium channel , biology , computational biology , signal transduction , biochemistry , enzyme , organic chemistry

In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on downstream cellular signaling controlling important physiological functions.

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