What Can Population Calcium Imaging Tell Us About Neural Circuits?
Author(s) -
Alex C. Kwan
Publication year - 2008
Publication title -
journal of neurophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.302
H-Index - 245
eISSN - 1522-1598
pISSN - 0022-3077
DOI - 10.1152/jn.91037.2008
Subject(s) - calcium imaging , biological neural network , neuroscience , computer science , electronic circuit , neural activity , neuronal circuits , population , artificial intelligence , calcium , psychology , materials science , engineering , electrical engineering , medicine , environmental health , metallurgy
Calcium imaging of bulk-loaded fluorescent indicators can be used to record the spiking activity of hundreds of neurons. Recent advances promise imaging technologies that are faster, more efficient, and applicable to awake animals, thereby moving imaging capabilities closer to the traditional strengths of multi-electrode arrays. This article reviews these technical achievements and discusses how they can help us achieve the goal of understanding neural circuits.
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