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Nonlinear effects of noradrenergic modulation of olfactory bulb function in adult rodents
Author(s) -
Christiane Linster,
Qiang Nai,
Matthew Ennis
Publication year - 2011
Publication title -
journal of neurophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.302
H-Index - 245
eISSN - 1522-1598
pISSN - 0022-3077
DOI - 10.1152/jn.00960.2010
Subject(s) - olfactory bulb , locus coeruleus , neuroscience , odor , olfactory system , norepinephrine , psychology , neurotransmission , olfactory memory , biology , central nervous system , receptor , dopamine , biochemistry
The mammalian main olfactory bulb receives a significant noradrenergic input from the locus coeruleus. Norepinephrine (NE) is involved in acquisition of conditioned odor preferences in neonatal animals, in some species-specific odor-dependent behaviors, and in adult odor perception. We provide a detailed review of the functional role of NE in adult rodent main olfactory bulb function. We include cellular, synaptic, network, and behavioral data and use computational simulations to tie these different types of data together.

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