The stochastic nature of action potential backpropagation in apical tuft dendrites | Zendy

Shaina M. Short | Zendy; Katerina D. Oikonomou | Zendy; WenLiang Zhou | Zendy; Corey D. Acker | Zendy; Marko Popović | Zendy; Dejan Zec̆ević | Zendy; Srdjan D. Antic | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The stochastic nature of action potential backpropagation in apical tuft dendrites

Author(s) -

Shaina M. Short,

Katerina D. Oikonomou,

WenLiang Zhou,

Corey D. Acker,

Marko Popović,

Dejan Zec̆ević,

Srdjan D. Antic

Publication year - 2017

Publication title -

journal of neurophysiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.302

H-Index - 245

eISSN - 1522-1598

pISSN - 0022-3077

DOI - 10.1152/jn.00800.2016

Subject(s) - tuft , dendritic spike , bursting , apical dendrite , soma , biophysics , neuroscience , chemistry , dendritic spine , patch clamp , electrophysiology , biology , excitatory postsynaptic potential , physics , hippocampal formation , inhibitory postsynaptic potential , thermodynamics

The bAP-Ca 2+ signal amplitudes in some apical tuft branches randomly vary from moment to moment. In repetitive measurements, successful AP invasions are followed by complete failures. Passive spread of voltage from the apical trunk into the tuft occasionally reaches the threshold for local Na + spike, resulting in stronger Ca 2+ influx. During a burst of three somatic APs, the peak of dendritic Ca 2+ in the apical tuft occurs with a delay of 20-50 ms depending on AP frequency.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research