Case studies in neuroscience: deep brain stimulation changes upper limb cortical motor maps in dystonia | Zendy

Nicholas D. J. Strzalkowski | Zendy; Rachel E. Sondergaard | Zendy; Liu Shi Gan | Zendy; Zelma H. T. Kiss | Zendy

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Case studies in neuroscience: deep brain stimulation changes upper limb cortical motor maps in dystonia

Author(s) -

Nicholas D. J. Strzalkowski,

Rachel E. Sondergaard,

Liu Shi Gan,

Zelma H. T. Kiss

Publication year - 2020

Publication title -

journal of neurophysiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.302

H-Index - 245

eISSN - 1522-1598

pISSN - 0022-3077

DOI - 10.1152/jn.00159.2020

Subject(s) - transcranial magnetic stimulation , deep brain stimulation , neuroscience , dystonia , cervical dystonia , stimulation , motor cortex , globus pallidus , upper limb , brain stimulation , medicine , psychology , physical medicine and rehabilitation , basal ganglia , parkinson's disease , central nervous system , pathology , disease

Neuronavigated robotic transcranial magnetic stimulation was used to investigate changes in upper limb muscle representation in a cervical dystonia patient before and at four time points up to 314 days after globus pallidus pars interna deep brain stimulation (GPi-DBS). GPi-DBS altered excitability and motor cortical representation of upper limb muscles; however, these changes were not associated with clinical improvement.

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