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Fetal alcohol exposure reduces responsiveness of taste nerves and trigeminal chemosensory neurons to ethanol and its flavor components
Author(s) -
John I. Glendinning,
Joyce Tang,
Ana Allende,
Bruce P. Bryant,
Lisa M. Youngentob,
Steven L. Youngentob
Publication year - 2017
Publication title -
journal of neurophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.302
H-Index - 245
eISSN - 1522-1598
pISSN - 0022-3077
DOI - 10.1152/jn.00108.2017
Subject(s) - taste , ethanol , alcohol , trigeminal nerve , flavor , fetal alcohol , fetus , neuroscience , anesthesia , medicine , psychology , chemistry , pregnancy , biology , biochemistry , pathology , genetics
Pregnant mothers are advised to avoid alcohol. This is because even small amounts of alcohol can alter fetal brain development and increase the risk of adolescent alcohol abuse. We asked how fetal alcohol exposure (FAE) produces the latter effect in adolescent rats by measuring responsiveness of taste nerves and trigeminal chemosensory neurons. We found that FAE substantially reduced taste and trigeminal responsiveness to ethanol and its flavor components.

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