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The current study demonstrates that olfactory receptor 78 (Olfr78), a G protein-coupled receptor, is an integral component of the hypoxic sensing mechanism of the carotid body to a wide range of low oxygen levels, but not severe hypoxia, and that Olfr78 participation does not require either lactate or any other short-chain fatty acids, proposed ligands of Olfr78.

Olfactory receptor 78 participates in carotid body response to a wide range of low O2 levels but not severe hypoxia

Olfactory receptor 78 participates in carotid body response to a wide range of low O₂ levels but not severe hypoxia