Balancing between stiff and soft: a life-saving compromise for lung epithelium in lung injury | Zendy

Konstantin G. Birukov | Zendy

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Balancing between stiff and soft: a life-saving compromise for lung epithelium in lung injury

Author(s) -

Konstantin G. Birukov

Publication year - 2014

Publication title -

journal of applied physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.253

H-Index - 229

eISSN - 8750-7587

pISSN - 1522-1601

DOI - 10.1152/japplphysiol.00912.2014

Subject(s) - extracellular matrix , fibrosis , myofibroblast , idiopathic pulmonary fibrosis , pathology , lung , pulmonary fibrosis , focal adhesion , tumor microenvironment , medicine , microbiology and biotechnology , immunology , biology , cancer research , signal transduction , immune system

mechanical properties of the extracellular matrix play a much more important role in cell differentiation ([3][1]) or responses of differentiated cells to various injurious insults ([1][2], [6][3]) than was previously thought. Cells can sense the stiffness of surrounding matrix and respond to

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