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whether intermittent hypoxia (IH)—the hallmark of obstructive sleep apnea (OSA)—is detrimental, protective, or both, is a fundamental question. The literature associating OSA with cardiovascular and other comorbidities is overwhelming, yet it is not clear whether IH also exerts protective

journal of applied physiology

The double-edged sword of intermittent hypoxia—can intermittent hypoxia be both deleterious and protective in OSA? Focus on “Frequency and magnitude of intermittent hypoxia modulate endothelial wound healing in a cell culture model of sleep apnea”