Effect of neuromuscular electrical stimulation on skeletal muscle size and function in patients with breast cancer receiving chemotherapy | Zendy

Michael J. Toth | Zendy; Thomas B. Voigt | Zendy; Timothy W. Tourville | Zendy; Shan M. Prior | Zendy; Blas A. Guigni | Zendy; Axel V. Schlosberg | Zendy; Isaac Smith | Zendy; Taylor J. Forest | Zendy; Peter A. Kaufman | Zendy; Marie Wood | Zendy; Hibba tul Rehman | Zendy; Kim Dittus | Zendy

Open Access

Effect of neuromuscular electrical stimulation on skeletal muscle size and function in patients with breast cancer receiving chemotherapy

Author(s) -

Michael J. Toth,

Thomas B. Voigt,

Timothy W. Tourville,

Shan M. Prior,

Blas A. Guigni,

Axel V. Schlosberg,

Isaac Smith,

Taylor J. Forest,

Peter A. Kaufman,

Marie Wood,

Hibba tul Rehman,

Kim Dittus

Publication year - 2020

Publication title -

journal of applied physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.253

H-Index - 229

eISSN - 8750-7587

pISSN - 1522-1601

DOI - 10.1152/japplphysiol.00203.2020

Subject(s) - contractility , stimulation , medicine , skeletal muscle , muscle hypertrophy , breast cancer , muscle fibre , cancer , cardiology , endocrinology

This is the first study to evaluate whether neuromuscular electrical stimulation (NMES) can be used as an exercise surrogate to improve skeletal muscle fiber size or function in cancer patients receiving treatment. We show that NMES promoted muscle fiber hypertrophy and fiber types shift but had minimal effects on single-fiber contractility and reduced subsarcolemmal mitochondria.

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