Coronary and cerebral metabolism-blood flow coupling and pulmonary alveolar ventilation-blood flow coupling may be disabled during acute carbon monoxide poisoning | Zendy

Ronald F. Coburn | Zendy

Open Access

Coronary and cerebral metabolism-blood flow coupling and pulmonary alveolar ventilation-blood flow coupling may be disabled during acute carbon monoxide poisoning

Author(s) -

Ronald F. Coburn

Publication year - 2020

Publication title -

journal of applied physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.253

H-Index - 229

eISSN - 8750-7587

pISSN - 1522-1601

DOI - 10.1152/japplphysiol.00172.2020

Subject(s) - blood flow , respiration , carbon monoxide , cerebral blood flow , hypoxia (environmental) , ventilation (architecture) , carbon monoxide poisoning , lung , hypercapnia , cardiology , anesthesia , respiratory system , medicine , chemistry , oxygen , poison control , anatomy , biochemistry , emergency medicine , mechanical engineering , organic chemistry , engineering , catalysis

This article introduces and supports a postulate that the tissue hypoxia component of carbon monoxide poisoning results in part from impairment of physiological adaptation mechanisms whereby tissues can match regional blood flow to O 2 uptake, and the lung can match regional blood flow to alveolar ventilation.

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