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Effect of nasal airway nonlinearities on oscillometric resistance measurements in infants
Author(s) -
Bence Radics,
Gergely Makan,
Thibault Coppens,
Nicolás André,
C. Page,
Loïc Dégrugilliers,
Sam Bayat,
Zoltán Gingl,
Zita Gyurkovits,
Tivadar M. Tóth,
Zoltán Hantos
Publication year - 2020
Publication title -
journal of applied physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.253
H-Index - 229
eISSN - 8750-7587
pISSN - 1522-1601
DOI - 10.1152/japplphysiol.00128.2020
Subject(s) - airway resistance , acceleration , airway , respiratory system , in vivo , biomedical engineering , flow resistance , medicine , materials science , flow (mathematics) , anesthesia , physics , mechanics , biology , microbiology and biotechnology , classical mechanics
Oscillometric measurements of respiratory system resistance (R rs ) in infants are usually made via the nasal pathways, which not only significantly contribute to overall R rs but also introduce marked flow acceleration-dependent distortions. Here, we propose a method for correcting flow acceleration-dependent nonlinearity error based on in vitro measurements in 3D-printed upper airway casts of infants as well as in vivo measurements. This correction can be adapted to estimate R rs from a single intrabreath oscillometric measurement.

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