Common mechanisms for the adaptive responses to exercise and heat stress
Author(s) -
Lisa R. Leon
Publication year - 2016
Publication title -
journal of applied physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.253
H-Index - 229
eISSN - 8750-7587
pISSN - 1522-1601
DOI - 10.1152/japplphysiol.00113.2016
Subject(s) - heat stress , physical exercise , psychology , medicine , physical medicine and rehabilitation , physical therapy , biology , zoology
In this Highlighted Topic we present five reviews that explore the molecular mechanisms mediating adaptive and maladaptive responses to exercise and environmental heat stress. Energetic stress, including changes in metabolic status, production of reactive oxygen species and increased temperature can all present significant challenges to cellular homeostasis that evoke cytoprotective mechanisms. Transcriptional changes form the basis of many adaptations with recent evidence suggesting epigenetics improves tolerance to a multitude of dissimilar stressors.
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