Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone | Zendy

Satish Rattan | Zendy

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Ca²⁺/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone

Author(s) -

Satish Rattan

Publication year - 2016

Publication title -

ajp gastrointestinal and liver physiology

Language(s) - English

Resource type - Journals

eISSN - 1522-1547

pISSN - 0193-1857

DOI - 10.1152/ajpgi.00370.2016

Subject(s) - calmodulin , internal anal sphincter , smooth muscle , rhoa , tone (literature) , anatomy , physics , chemistry , biophysics , microbiology and biotechnology , biology , medicine , endocrinology , signal transduction , nuclear magnetic resonance , anal canal , enzyme , rectum , art , literature

it is well known that smooth muscle contraction, whether spontaneous or following pharmacological stimulation, occurs in two phases: the initial phasic followed by the tonic phase ([1][1], [2][2], [5][3], [6][4], [11][5], [12][6], [14][7], [16][8], [17][9], [22][10], [23][11], [25][12], [33][13], [

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