Extracellular vesicles in liver diseases | Zendy

Sayantan Maji | Zendy; Akiko Matsuda | Zendy; Irene K. Yan | Zendy; Mansi Parasramka | Zendy; Tushar Patel | Zendy

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Extracellular vesicles in liver diseases

Author(s) -

Sayantan Maji,

Akiko Matsuda,

Irene K. Yan,

Mansi Parasramka,

Tushar Patel

Publication year - 2016

Publication title -

ajp gastrointestinal and liver physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.644

H-Index - 169

eISSN - 1522-1547

pISSN - 0193-1857

DOI - 10.1152/ajpgi.00216.2016

Subject(s) - extracellular vesicles , extracellular , intracellular , vesicle , extracellular vesicle , microvesicles , liver disease , microbiology and biotechnology , biology , cd81 , immunology , biochemistry , membrane , microrna , hepatitis c virus , gene , virus

Extracellular vesicles (EVs) are membrane-bound vesicles that are released by cells into their extracellular environment, have selective enrichment of specific proteins and RNA, and can mediate intercellular communication. In this review we highlight recent observations of the role of EVs in liver injury, viral hepatitis, alcoholic or nonalcoholic liver disease, biliary tract disease, and liver cancers. Potential applications as markers of diseases or for therapeutic applications are outlined to emphasize the new opportunities that are arising from the study of EVs.

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