Motoring down the microvilli. Focus on “PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI” | Zendy

Alicia A. McDonough | Zendy

Open Access

Motoring down the microvilli. Focus on “PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI”

Author(s) -

Alicia A. McDonough

Publication year - 2009

Publication title -

ajp cell physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.432

H-Index - 181

eISSN - 1522-1563

pISSN - 0363-6143

DOI - 10.1152/ajpcell.00423.2009

Subject(s) - apical membrane , cotransporter , internalization , chemistry , actin cytoskeleton , brush border , reabsorption , actin , microbiology and biotechnology , cytoskeleton , biochemistry , sodium , biophysics , biology , cell , membrane , vesicle , organic chemistry

the kidneys filter 120 ml/min at the renal glomeruli, and two thirds of this ultrafiltrate is reabsorbed in the proximal tubule. To accomplish this high rate of reabsorption, the proximal tubule has a tall brush border formed by densely packed microvilli each with a core of actin filaments bundled

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