Chronic ethanol exposure closes the door to vitamin C in pancreatic acinar cells. Focus on “Uptake of ascorbic acid by pancreatic acinar cells is negatively impacted by chronic alcohol exposure”
Author(s) -
Alexander L. Ticho,
Waddah A. Alrefai
Publication year - 2016
Publication title -
ajp cell physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.432
H-Index - 181
eISSN - 1522-1563
pISSN - 0363-6143
DOI - 10.1152/ajpcell.00149.2016
Subject(s) - ascorbic acid , acinar cell , vitamin , ethanol , vitamin c , chronic alcoholic , acinus , chemistry , medicine , pancreas , endocrinology , cancer research , biochemistry , food science
pancreatitis is an inflammatory disease that causes significant health care burden worldwide. Treatment of pancreatitis is severely limited by a lack of understanding of the molecular mechanisms underlying the pathophysiology ([2][1]). Recent evidence has implicated oxidative stress within
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