Beyond translation: the renal phosphate census. Focus on “Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule” | Zendy

Jennifer L. Pluznick | Zendy

Open Access

Beyond translation: the renal phosphate census. Focus on “Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule”

Author(s) -

Jennifer L. Pluznick

Publication year - 2011

Publication title -

ajp cell physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.432

H-Index - 181

eISSN - 1522-1563

pISSN - 0363-6143

DOI - 10.1152/ajpcell.00009.2011

Subject(s) - distal convoluted tubule , reabsorption , nephron , apical membrane , microbiology and biotechnology , podocyte , renal cortex , tubule , kidney , biology , chemistry , medicine , endocrinology , biochemistry , membrane , proteinuria

the addition of a single phosphate group to a protein can cause dramatic and varied changes in its function: it can change an ion channel's open probability ([31][1]), trigger the activation of an entire signaling cascade ([17][2]), or cause a protein to translocate to the cell surface ([30][3]).

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