Terahertz Chemical Imaging of a Multicomponent Tablet in Pharmaceutical Applications
Author(s) -
Katsuhiro Ajito,
Yuko Ueno,
Ho-Jin Song,
Jae-Young Kim,
Emi Tamechika,
Naoya Kukutsu,
Waree Limwikrant,
Keiji Yamamoto,
Kunikazu Moribe
Publication year - 2013
Publication title -
ecs transactions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.235
H-Index - 52
eISSN - 1938-6737
pISSN - 1938-5862
DOI - 10.1149/05012.0109ecst
Subject(s) - terahertz radiation , cryostat , chemical imaging , materials science , sample (material) , analytical chemistry (journal) , nanotechnology , optoelectronics , chemistry , computer science , chromatography , physics , hyperspectral imaging , condensed matter physics , superconductivity , artificial intelligence
We describe multicomponent chemical analysis of pharmaceuticals using a sample chamber cooled by a cryostat. THz chemical imaging (TCI) measurement at low temperature sharpens spectral peaks and/or shifts peak frequencies, enabling us to determine the distribution of several kinds of pharmaceutical chemicals within a tablet.
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