Open AccessBRCAMutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations
Author(s) -
Mai Elezaby,
Brittany Lees,
Katherine E. Maturen,
Lisa Barroilhet,
Kari B. Wisinski,
Sarina Schrager,
Lee G. Wilke,
Elizabeth A. Sadowski
Publication year - 2019
Publication title -
radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.118
H-Index - 295
eISSN - 1527-1315
pISSN - 0033-8419
DOI - 10.1148/radiol.2019181814
Subject(s) - medicine , ovarian cancer , brca mutation , breast cancer , genetic testing , oncology , mutation , population , gynecology , cancer , bioinformatics , gene , genetics , environmental health , biology
Patients who carry the BRCA 1 and BRCA 2 gene mutations have an underlying genetic predisposition for breast and ovarian cancers. These deleterious genetic mutations are the most common genes implicated in hereditary breast and ovarian cancers. This monograph summarizes the evidence behind current screening recommendations, reviews imaging protocols specific to this patient population, and illustrates some of the imaging nuances of breast and ovarian cancers in this clinical setting.