Open AccessMeasurement of Tissue Interstitial Volume in Healthy Patients and Those with Amyloidosis with Equilibrium Contrast-enhanced MR Imaging
Author(s) -
Steve Bandula,
Sanjay M. Banypersad,
Daniel Sado,
Andrew Flett,
Shonit Punwani,
Stuart A. Taylor,
Philip N. Hawkins,
James Moon
Publication year - 2013
Publication title -
radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.118
H-Index - 295
eISSN - 1527-1315
pISSN - 0033-8419
DOI - 10.1148/radiol.13121889
Subject(s) - medicine , amyloidosis , magnetic resonance imaging , spleen , pathology , amyloid (mycology) , gastroenterology , nuclear medicine , radiology
To investigate equilibrium contrast material-enhanced magnetic resonance (MR) imaging measurement of extracellular volume (ECV) fraction within healthy abdominal tissues and to test the hypotheses that tissue ECV in systemic amyloid light-chain (AL) amyloidosis is greater than in healthy patients and show that this increase correlates with organ amyloid burden.