Open AccessVasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase
Author(s) -
Henry S. Su,
Matthias Nahrendorf,
Peter Panizzi,
Michael O. Breckwoldt,
Elisenda Rodrı́guez,
Yoshiko Iwamoto,
Elena Aikawa,
Ralph Weissleder,
John W. Chen
Publication year - 2012
Publication title -
radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.118
H-Index - 295
eISSN - 1527-1315
pISSN - 0033-8419
DOI - 10.1148/radiol.11110040
Subject(s) - myeloperoxidase , medicine , vasculitis , pathology , magnetic resonance imaging , molecular imaging , inflammation , in vivo , nuclear medicine , radiology , disease , microbiology and biotechnology , biology
To determine if a molecular imaging approach targeting the highly oxidative enzyme myeloperoxidase (MPO) can help noninvasively identify and confirm sites of vascular wall inflammation in a murine model of vasculitis.