Open AccessFrom the archives of the AFIP. Malignant germ cell tumors of the ovary: radiologic-pathologic correlation.
Author(s) -
H M Brammer,
James R. Buck,
W S Hayes,
Sunil G. Sheth,
F. A. Tavassoli
Publication year - 1990
Publication title -
radiographics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.866
H-Index - 172
eISSN - 1527-1323
pISSN - 0271-5333
DOI - 10.1148/radiographics.10.4.2165627
Subject(s) - medicine , dysgerminoma , germ cell tumors , immature teratoma , ovary , pathology , teratoma , germ cell , endodermal sinus tumor , human chorionic gonadotropin , neoplasm , chemotherapy , biology , hormone , biochemistry , gene
Malignant germ cell tumors are the most common malignant ovarian neoplasms in girls and young women. The most well known of these neoplasms are dysgerminoma, immature teratoma, endodermal sinus tumor, and a mixture of two or more of these elements. All malignant germ cell tumors, especially immature teratoma, can be associated with mature (benign) teratoma. These tumors are generally large and have a complex but predominantly solid appearance on cross-sectional images. Elevated serum alpha-fetoprotein and human chorionic gonadotropin levels can help establish the diagnosis. Cystic areas of calcifications suggestive of mature teratoma do not exclude a co-existing malignant neoplasm.