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A Large Scale Dynamical System Immune Network Model with Finite Connectivity
Author(s) -
Tatsuya Uezu,
Chihiro Kadono,
J. P. L. Hatchett,
A C C Coolen
Publication year - 2006
Publication title -
progress of theoretical physics supplement
Language(s) - English
Resource type - Journals
ISSN - 0375-9687
DOI - 10.1143/ptps.161.385
Subject(s) - immune system , scale (ratio) , statistical physics , computer science , mathematics , physics , biology , immunology , quantum mechanics
We study a model of an idiotypic immune network which was introduced by N. K. Jerne. It is known that in immune systems there generally exist several kinds of immune cells which can recognize any particular antigen. Taking this fact into account and assuming that each cell interacts with only a finite number of other cells, we analyze a large scale immune network via both numerical simulations and statistical mechanical methods, and show that the distribution of the concentrations of antibodies becomes non-trivial for a range of values of the strength of the interaction and the connectivity.

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