Stimulated Raman scattering microscopy for rapid brain tumor histology | Zendy

Yifan Yang | Zendy; Lingchao Chen | Zendy; Minbiao Ji | Zendy

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Stimulated Raman scattering microscopy for rapid brain tumor histology

Author(s) -

Yifan Yang,

Lingchao Chen,

Minbiao Ji

Publication year - 2017

Publication title -

journal of innovative optical health sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.421

H-Index - 24

eISSN - 1793-5458

pISSN - 1793-7205

DOI - 10.1142/s1793545817300105

Subject(s) - histology , microscopy , pathology , brain tumor , neuroimaging , virtual microscopy , raman scattering , focus (optics) , medicine , raman spectroscopy , biomedical engineering , neuroscience , biology , optics , physics

Rapid histology of brain tissues with sufficient diagnostic information has the great potential to aid neurosurgeons during operations. Stimulated Raman Scattering (SRS) microscopy is an emerging label-free imaging technique, with the intrinsic chemical resolutions to delineate brain tumors from normal tissues without the need of time-consuming tissue processing. Growing number of studies have shown SRS as a “virtual histology” tool for rapid diagnosis of various types of brain tumors. In this review, we focus on the basic principles and current developments of SRS microscopy, as well as its applications for brain tumor imaging

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