Open AccessInfluence of absorption in linear polarization imaging of melanoma tissues
Author(s) -
Dong-Zhi Li,
Honghui He,
Nan Zeng,
Weidong Xie,
Ran Liao,
Jian Wu,
Yonghong He,
Hui Ma
Publication year - 2014
Publication title -
journal of innovative optical health sciences/journal of innovation in optical health science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 24
eISSN - 1793-5458
pISSN - 1793-7205
DOI - 10.1142/s1793545814500096
Subject(s) - polarization (electrochemistry) , scattering , optics , monte carlo method , linear polarization , materials science , molecular physics , physics , chemistry , mathematics , laser , statistics
The contrast mechanism of different polarization imaging techniques for melanoma in mouse skin is studied using both experiments and Monte Carlo simulations. Total intensity, linear polarization difference imaging (DPI), degree of polarization imaging (DOPI) and rotating linear polarization imaging (RLPI) are applied and the relative contrasts of these polarization imaging methods between the normal and cancerous tissues are compared. A two-layer absorption-scattering model is proposed to explain the contrast mechanism of the polarization imaging for melanoma. By taking into account of both scattering of symmetrical and asymmetrical scatterers and absorption of inter-scatterer medium, the two-layer model reproduces the relative contrasts for polarization images observed in experiments. The simulation results also show that, the parameters of polarization imaging change more dramatically with the variation of absorption in the bottom layer than the top layer