English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The crystal structures of six derivatives of the C α,α -dialkylated α-aminoacid residue 1-aminocyclopentane-1-carboxylic acid (Acc 5 ) have been determined. These are Z-Acc 5 -OH, Z-Acc 5 -OH acetone hemi-solvate, Fmoc-Acc 5 -OH, mClAc-Acc 5 -OH, pBrBz-Acc 5 -OH, and the 5(4H)-oxazolone from pBrBz-Acc 5 -OH. The values determined for the torsion angles about the [Formula: see text] and C α —CO (ψ) bonds correspond to folded, potentially α/3 10 -helical conformations for the Acc 5  residue of Z-Acc 5 -OH, Z-Acc 5 -OH acetone hemi-solvate, mClAc-Acc 5 -OH, and pBrBz-Acc 5 -OH. The structure of Fmoc-Acc 5 -OH, however, is unusual in having a semi-extended conformation for the [Formula: see text], ψ angles, accompanied by a cis arrangement of the amide group of the secondary urethane moiety. The dependence of the N—C α —C′ bond angle on the ψ torsion angle and the asymmetry at the C α  atom are relevant features of the Acc 5  residues. The position of the cyclopentyl ring relative to the peptide chain and its puckering parameters for the six compounds are also discussed.

canadian journal of chemistry

Linear oligopeptides. 188.Crystallographic characterization of the conformation of the 1-aminocyclopentane-1-carboxylic acid residue in simple derivatives