Open AccessAlkylation of tert-butyl lithiohydrazones of aldehydes and ketones
Author(s) -
Shao-Fang Wang,
John Warkentin
Publication year - 1988
Publication title -
canadian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 68
eISSN - 1480-3291
pISSN - 0008-4042
DOI - 10.1139/v88-358
Subject(s) - chemistry , alkylation , acetaldehyde , butyllithium , acetone , formaldehyde , halide , alkyl , organic chemistry , medicinal chemistry , catalysis , ethanol
Treatment of the tert-butylhydrazones of formaldehyde, acetaldehyde, and acetone with butyllithium afforded the corresponding tert-butyl lithiohydrazones, which were alkylated with alkyl, allyl, and benzyl halides. Fourteen new tert-butylazo compounds were prepared in yields ranging from 38 to 86%.