Open AccessSynthèses des alkyl-1 cyclanols fonctionnalisés aux positions α, β et γ de la chaîne hydrocarbonée
Author(s) -
P. Cane,
Michel Belley,
George Fytas,
J. Plamondon
Publication year - 1988
Publication title -
canadian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 68
eISSN - 1480-3291
pISSN - 0008-4042
DOI - 10.1139/v88-026
Subject(s) - chemistry , hydrocarbon , alkyl , medicinal chemistry , organic chemistry
We have developed a general and versatile synthesis of N,N-dialkylaminoalkyl-, 1-chloroalkyl-, 1-phenoxyalkyl-, 1-thiophenoxyalkyl-, 1-diethyoxyalkyl-, and 1-(1,3-dithiolane)alkylcyclanols in good yields by the reaction of α,ω-bis(bromomagnesio)alkanes with the corresponding functionalized carboxylic acid esters.